Physical mechanisms of chromatin spatial organization
نویسندگان
چکیده
منابع مشابه
The links between chromatin spatial organization and biological function
During the last few years, there has been a rapid increase in our knowledge of how chromatin is organized inside the nucleus. Techniques such as FISH (fluorescence in situ hybridization) have proved that chromosomes organize themselves in so-called CTs (chromosome territories). In addition, newly developed 3C (chromatin conformation capture) techniques have revealed that certain chromosomal reg...
متن کاملExploring chromatin organization mechanisms through its dynamic properties
The organization of the genome in the nucleus is believed to be crucial for different cellular functions. It is known that chromosomes fold into distinct territories, but little is known about the mechanisms that maintain these territories. To explore these mechanisms, we used various live-cell imaging methods, including single particle tracking to characterize the diffusion properties of diffe...
متن کاملChromatin Organization
Although the Victorian proverb ‘‘everything in its place and a place for everything’’ is meant for orderly households, it could just as easily describe the organization of eukaryotic genomes. This issue’s Select profiles articles that reveal new insights into how DNA is packaged and partitioned into three-dimensional (3D) structures throughout the life of a cell, shedding new light on how inter...
متن کاملRole of physical mechanisms in biological self-organization.
Organs form during morphogenesis, the process that gives rise to specialized biological structures of specific shape and function in early embryonic development. Morphogenesis is under strict genetic control, but shape evolution itself is a physical process. Here we report the results of experimental and modeling biophysical studies on in vitro biological structure formation. Experimentally, by...
متن کاملrecognition of the homeostasis mechanisms in the spatial - physical structure of the city -
the study of the historical development of our cities reveal a heterogeneous growth, particularly in the case of large cities. such a growth has been endemic to all the developing world. the new movement has been the determinant factor in changing the evolutionary process of shaping homgenous cities of the past. in the ambiguity and confusion of loosing traditional thoughts, looking for homogen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FEBS Journal
سال: 2021
ISSN: 1742-464X,1742-4658
DOI: 10.1111/febs.15762